Environmental and Occupational Short-Term Exposure to Airborne Particles and FEV1 and FVC in Healthy Adults: A Systematic Review and Meta-Analysis

BACKGROUND: No study has compared the respiratory effects of environmental and occupational particulate exposure in healthy adults. METHODS: We estimated, by a systematic review and meta-analysis, the associations between short term exposures to fine particles (PM2.5 and PM4) and certain parameters of lung function (FEV1 and FVC) in healthy adults. RESULTS: In total, 33 and 14 studies were included in the qualitative synthesis and meta-analyses, respectively. In environmental studies, a 10 µg/m3 increase in PM2.5 was associated with an FEV1 reduction of 7.63 mL (95% CI: -10.62 to -4.63 mL). In occupational studies, an increase of 10 µg/m3 in PM4 was associated with an FEV1 reduction of 0.87 mL (95% CI: -1.36 to -0.37 mL). Similar results were observed with FVC. CONCLUSIONS: Both occupational and environmental short-term exposures to fine particles are associated with reductions in FEV1 and FVC in healthy adults.
Auteurs (Zotero)
da Silveira Fleck, Alan; Sadoine, Margaux L.; Buteau, Stéphane; Suarthana, Eva; Debia, Maximilien; Smargiassi, Audrey
Date de publication (Zotero)
octobre, 2021